νοσος parkinson

Bibliographic Records

Objective clinical evaluation of the patient with Parkinson’s disease: the usefulness of various rating scales

Assessment of Parkinson’s disease (PD) is a complex process as a consequence of the variety of motor and non-motor symptoms as well as treatment complications, that can be present in a patient. A significant number of rating scales and questionnaires,

Fatigue assessment in Parkinson’s disease

Background: Fatigue is a major non-specific symptom in a number of disorders including Parkinson’s disease (PD). Fatigue is a vague concept and although it is understood by all, it is hard to define and much more difficult to measure precisely.

Cognitive impairement and dementia in Parkinson’s disease

Dementia in patients suffering from Parkinson’s disease (PD) has long been considered unrelated to the disease. The constant improvement in the management of motor symptoms and the consequent increase in the life expectancy of these patients brought out cognitive impairment

Plasma ascorbate levels in Parkinsori s disease and vascular Parkinsonism

Oxidative stress is an important mechanism of cell death in Parkinson s disease (PD) and brain ischemia, which seems to contribute to vascular injury in atheromatosis. Ascorbate is an important water-soluble antioxidant and neuroprotective agent. By means of high performance

Apolipoprotein E genotypes in degenerative disorders of the CNS

Apolipoprotein E (Αpo-Ε) has attracted considerable interest due to its possible implication in the pathogenesis of various neurodegenerative disorders.The Αpo-Ε gene, located on chromosome 19, is polymorphic, with ε2, ε3, ε4 being the most common alleles. Since the Αpo-Ε ε4

Pain in Parkinson’s disease: Classification and therapeutic approaches

Pain, one of the sensory symptoms of Parkinson’s disease, is a frequent yet poorly understood non-motor symptom of the disease, sometimes severe enough to overshadow the motor symptoms of the disorder. In this review article, we consider pain that can

Sleep disorders in Parkinson’s disease

Sleep symptoms in Parkinson’s disease (PD) are frequent and have multifactorial origins. Frequent causes of these disorders include primary involvement of sleep/wake regulating centers in the brainstem, nocturnal manifestations of motor and dysautonomic signs and medication effects. The study of

An observational prospective study investigating the characteristics of nocturnal symptoms, sleep disorders and daytime sleepiness in patients with Parkinson’s disease under treatment with levodopa.

Introduction.The aim of the present study is to investigate the characteristics of nocturnal symptoms, sleep disorders and daytime sleepiness in patients with Parkinson’s disease under treatment with levodopa.Materials and Methods. This is a multi-center, non-interventional, observational study involving 277 outpatients

Telemedicine in neurodegenerative diseases: Opportunities and challenges

As population ages, the prevalence of neurodegenerative diseases, including Alzheimer’s and Parkinson’s disease,will continue to rise. Disruption of daily functioning often contributes to increased difficulties in accessibility to appropriate healthcare services. Patients in remote areas are affected to a higher